CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7418
Family Name C-C chemokine receptor type 2 and C-C chemokine receptor type 5 ligand [(1S,3R)-3-[[(3S,4S)-3-methyloxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone family
No. of Seeds 4 No. of Other Members 12
Family Centroid CFAMM00379883 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and C-C chemokine receptor type 5 Binder Superfamily 2
Class Class 3470

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 2 ligand (1S,3R)-N-[[3,5-bis(trifl... 8 8


External ID

Functional Category

Molecule Name

CFAMM00379892 CHEMBL1683067 Bioactive [(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
CFAMM00379883 CHEMBL1683059 Bioactive [(1S,3R)-3-[[(3S,4S)-3-methyloxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
CFAMM00379889 CHEMBL1683060 Bioactive [(1S,3R)-3-[[(3R,4R)-3-methyloxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
CFAMM00379888 CHEMBL1683063 Bioactive [(1S,3R)-3-[[(3S,4S)-3-ethyloxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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