CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7419
Family Name C-C chemokine receptor type 2 and C-C chemokine receptor type 5 ligand [(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone family
No. of Seeds 5 No. of Other Members 20
Family Centroid CFAMM00379905 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 2
Class Class 1006

Cousin Family NamesSeedsMembers
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 1
C-C chemokine receptor type 1 ligand [(1S)-3-[[(3S,4S)-3-metho... 1 15
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0


External ID

Functional Category

Molecule Name

CFAMM00379900 CHEMBL1782377 Bioactive [(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]-methylamino]-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
CFAMM00379906 CHEMBL1683077 Bioactive [(1S,3R)-1-ethyl-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]cyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
CFAMM00379905 CHEMBL1683074 Bioactive [(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
CFAMM00379904 CHEMBL1683073 Bioactive [(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[6-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
CFAMM00379901 CHEMBL1683190 Bioactive [(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-(2,2,2-trifluoroethyl)cyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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