CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7425
Family Name Prostaglandin E synthase and Aldo-keto reductase family 1 member C3 inhibitor AGN-PC-09QN57 family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00379944 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 Ligand A-425619 Superfamily
Class Class 825

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 158
Transient receptor potential cation channel subfamily V member... 16 295
Amg 423 family 7 47
ABC294640 family 5 75
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 9
Transient receptor potential cation channel subfamily V member... 3 1
Metabotropic glutamate receptor 5 ligand [(E)-(1,2-dicyclohexy... 1 4
Prostaglandin E synthase inhibitor AGN-PC-09QHBK family 3 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 4
Cholesteryl ester transfer protein inhibitor 1-[(1S)-1-(5-chlo... 1 4
Nociceptin receptor and Mu-type opioid receptor ligand N-[(1R,... 4 2
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 0
Sterol O-acyltransferase 1 inhibitor SureCN7073167 family 4 2
Reverse transcriptase/RNaseH inhibitor (4s)-6-chloro-4-cyclopr... 5 3


External ID

Functional Category

Molecule Name

CFAMM00379946 CHEMBL1683217 Bioactive AGN-PC-07NA3O
CFAMM00379945 CHEMBL1683214 Bioactive AGN-PC-09QH9F
CFAMM00379944 CHEMBL1683215 Bioactive AGN-PC-09QN57

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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