CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TFLH family
No. of Seeds 6 No. of Other Members 11
Family Centroid CFAMM00314884 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 and Thyrotropin receptor Binder Superfamily
Class Class 1554

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase Inhibitor SC-74020 Family 1 21
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-(3-p... 7 17
Kinesin-like protein KIF11 Inhibitor N-{4'-[(trifluoromethyl)s... 3 1
Fructose-1,6-bisphosphatase 1 Inhibitor 1-(4-aminophenylsulfon... 2 1
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 2
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1-(2-c... 1 1
C-C chemokine receptor type 5 ligand AC1L9YPM family 3 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 14
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand (1R,3... 2 13
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 3 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 0
C-C chemokine receptor type 3 ligand AGN-PC-073RNI family 2 2


External ID

Functional Category

Molecule Name

CFAMM00314897 CHEMBL1088351 Bioactive AGN-PC-04TFL8
CFAMM00314880 CHEMBL1088083 Bioactive AGN-PC-04TFLI
CFAMM00314889 CHEMBL1087723 Bioactive AGN-PC-07ZFOR
CFAMM00314886 CHEMBL1088227 Bioactive AGN-PC-07ZFO5
CFAMM00314885 CHEMBL1099390 Bioactive AGN-PC-04TFL9
CFAMM00314884 CHEMBL1088366 Bioactive AGN-PC-04TFLH

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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