CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7448
Family Name Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[4-[1-(dimethylamino)ethyl]-2-fluorophenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide family
No. of Seeds 16 No. of Other Members 5
Family Centroid CFAMM00380136 Functional Category Bioactive
Superfamily Coagulation factor X and Prostaglandin E2 receptor EP3 subtype Binder Superfamily
Class Class 289

Cousin Family NamesSeedsMembers
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-075DUK family 4 1
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Coagulation factor X inhibitor SureCN14490781 family 15 0
Coagulation factor X inhibitor SureCN4855529 family 6 0
Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N... 6 1


External ID

Functional Category

Molecule Name

CFAMM00380137 CHEMBL1689026 Bioactive SureCN4356792
CFAMM00380123 CHEMBL1684182 Bioactive SureCN5443029
CFAMM00380136 CHEMBL593354 Bioactive (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[4-[1-(dimethylamino)ethyl]-2-fluorophenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide
CFAMM00380122 CHEMBL1684188 Bioactive (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-(2-fluoro-4-pyrrolidin-2-ylphenyl)-2-oxopyrrolidin-3-yl]ethenesulfonamide
CFAMM00380135 CHEMBL1689029 Bioactive SureCN4637713
CFAMM00380128 CHEMBL1689018 Bioactive SureCN4171376
CFAMM00380121 CHEMBL595477 Bioactive SureCN5376200
CFAMM00380134 CHEMBL1684192 Bioactive (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[2-fluoro-4-[(2R)-pyrrolidin-2-yl]phenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide
CFAMM00380127 CHEMBL593584 Bioactive SureCN5375694
CFAMM00380133 CHEMBL1684179 Bioactive (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[1-(dimethylamino)-2,3-dihydro-1H-inden-5-yl]-2-oxopyrrolidin-3-yl]ethenesulfonamide
CFAMM00380126 CHEMBL1689013 Bioactive SureCN4175304
CFAMM00380139 CHEMBL1689023 Bioactive SureCN4183912
CFAMM00380119 CHEMBL1684193 Bioactive (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[2-fluoro-4-[(2S)-pyrrolidin-2-yl]phenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide
CFAMM00380125 CHEMBL1689014 Bioactive SureCN4164339
CFAMM00380138 CHEMBL1689022 Bioactive SureCN4183900
CFAMM00380131 CHEMBL594085 Bioactive SureCN6362738

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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