CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7449
Family Name Coagulation factor X inhibitor SureCN4172349 family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00380140 Functional Category Bioactive
Superfamily Coagulation factor X and Beta-lactamase Binder Superfamily
Class Class 1209

Cousin Family NamesSeedsMembers
Growth hormone receptor Ligand EP-51216 Family 34 390
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Cathepsin L1 inhibitor Bio2_000267 family 9 1
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 1 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Neuropeptide Y receptor type 5 ligand 2-(6-chloroindol-1-yl)-N... 4 23
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
Coagulation factor X and Prothrombin inhibitor SureCN8237487 f... 16 1
Coagulation factor X inhibitor 5-chloro-N-[1-[2-fluoro-4-(2-me... 2 5
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 3 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4


External ID

Functional Category

Molecule Name

CFAMM00380140 CHEMBL1689016 Bioactive SureCN4172349
CFAMM00380146 CHEMBL1689028 Bioactive SureCN4639287
CFAMM00380145 CHEMBL1684190 Bioactive 3-chloro-N-[(3S)-1-(2-fluoro-4-pyrrolidin-2-ylphenyl)-2-oxopyrrolidin-3-yl]-1H-indole-6-sulfonamide
CFAMM00380143 CHEMBL1684184 Bioactive SureCN5428069
CFAMM00380148 CHEMBL1689025 Bioactive SureCN4172366
CFAMM00380141 CHEMBL1684181 Bioactive SureCN5431197
CFAMM00380147 CHEMBL1689024 Bioactive SureCN4173064

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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