CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7456
Family Name Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dichloro-1H-benzimidazol-2-yl)pyrrolidin-1-yl]-3-[4-(3-pyridin-4-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]propan-1-one family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00380233 Functional Category Bioactive
Superfamily Lysosomal Pro-X carboxypeptidase and Aurora kinase A Binder Superfamily
Class Class 3234

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Platelet-activating factor receptor ligand SureCN9383514 family 4 1
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 3 5
Lysosomal Pro-X carboxypeptidase inhibitor 2-amino-N-[(2S)-1-[... 11 16
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... 3 21
Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dich... 2 0
Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dich... 2 2
Sonic hedgehog protein and Smoothened homolog inhibitor N-(4,4... 2 13
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 3-[3-... 4 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 3-[3-... 2 0
Lysosomal Pro-X carboxypeptidase inhibitor 1-[6-[(2S)-2-(5,6-d... 2 0
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380233 CHEMBL1684297 Bioactive 1-[(2S)-2-(5,6-dichloro-1H-benzimidazol-2-yl)pyrrolidin-1-yl]-3-[4-(3-pyridin-4-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]propan-1-one
CFAMM00380231 CHEMBL1684295 Bioactive 1-[(2S)-2-(5,6-dichloro-1H-benzimidazol-2-yl)pyrrolidin-1-yl]-3-[4-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]propan-1-one
CFAMM00380241 CHEMBL1684300 Bioactive 1-[(2S)-2-(5,6-dichloro-1H-benzimidazol-2-yl)pyrrolidin-1-yl]-3-[4-(3-quinolin-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]propan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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