CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7460
Family Name Glucocorticoid receptor and Progesterone receptor ligand [(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-3,4-dihydro-1H-quinolin-3-yl] N-benzylcarbamate family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00377599 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Progesterone receptor Binder Superfamily
Class Class 3193

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 9 3
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 7 14
Glucocorticoid receptor ligand SureCN5650626 family 17 25
Glucocorticoid receptor ligand SureCN4198717 family 5 0
Glucocorticoid receptor ligand SureCN4204659 family 2 0
Glucocorticoid receptor and Androgen receptor ligand AGN-PC-0A... 3 0
Glucocorticoid receptor ligand AGN-PC-0A9RHA family 1 2
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[2-(1H-ind... 1 0
Transporter and Sodium-dependent serotonin transporter inhibit... 2 1
CGMP-dependent protein kinase inhibitor methyl 2-[[4-[5-(4-flu... 6 1


External ID

Functional Category

Molecule Name

CFAMM00380252 CHEMBL1684341 Bioactive SureCN4193702
CFAMM00380251 CHEMBL1684353 Bioactive [(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-3,4-dihydro-1H-quinolin-3-yl] N-(4-cyanophenyl)carbamate
CFAMM00380250 CHEMBL1684347 Bioactive SureCN4195440

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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