CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7466
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor AGN-PC-0757DJ family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00380319 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter Binder Superfamily 7
Class Class 799

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Noradrenergic re-uptake and Serotonin re-uptake inhibitor phen... 18 41
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 4 10
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sodium-dependent dopamine transporter and Transporter inhibito... 4 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 2
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 7 16
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 7 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 11 2
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380319 CHEMBL168455 Bioactive AGN-PC-0757DJ
CFAMM00380318 CHEMBL169117 Bioactive 1-[3-(3-chloro-4-iodophenyl)-8-azabicyclo[3.2.1]octan-4-yl]propan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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