CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7472
Family Name Squalene synthase inhibitor AGN-PC-09M2X2 family
No. of Seeds 12 No. of Other Members 22
Family Centroid CFAMM00380496 Functional Category Bioactive
Superfamily Squalene synthase inhibitor AGN-PC-09M2X2 Superfamily
Class Class 367

Cousin Family NamesSeedsMembers
Squalene synthase Inhibitor Lapaquistat Acetate Family 27 38
Squalene synthase inhibitor (3S)-1-[4-[2,4-dichloro-N-(2,2-dim... 1 0
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand 2-amino-N-[(2R)-3-(2,4-dichloro... 5 5


External ID

Functional Category

Molecule Name

CFAMM00380505 CHEMBL1684994 Bioactive AGN-PC-09QGWY
CFAMM00380498 CHEMBL1685022 Bioactive AGN-PC-09QGXG
CFAMM00380497 CHEMBL1684849 Bioactive AGN-PC-09QHB1
CFAMM00380516 CHEMBL1684837 Bioactive AGN-PC-09QHRB
CFAMM00380496 CHEMBL1684826 Bioactive AGN-PC-09M2X2
CFAMM00380509 CHEMBL1684838 Bioactive AGN-PC-09QHRC
CFAMM00380514 CHEMBL1684833 Bioactive AGN-PC-09QMWC
CFAMM00380494 CHEMBL1684829 Bioactive AGN-PC-09QMWB
CFAMM00380513 CHEMBL1684832 Bioactive AGN-PC-09QIN8
CFAMM00380500 CHEMBL1684841 Bioactive AGN-PC-09QIN9
CFAMM00380506 CHEMBL1684993 Bioactive AGN-PC-09QM3B
CFAMM00380512 CHEMBL1684831 Bioactive AGN-PC-09QIN7

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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