CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7476
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(dimethylcarbamoyloxy)phenyl]-2-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)pyrimidin-4-yl]amino]propanoic acid family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00380582 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-5 Binder Superfamily 2
Class Class 1877

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Dihydrofolate reductase inhibitor 10-Oxaaminopterin family 1 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 4 40
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(3,5-di... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 12
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[3,4-di... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380582 CHEMBL1684970 Bioactive (2S)-3-[4-(dimethylcarbamoyloxy)phenyl]-2-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)pyrimidin-4-yl]amino]propanoic acid
CFAMM00380580 CHEMBL1684983 Bioactive (2S)-2-[[2-(diethylamino)-5-(3,5-dimethyl-1,2-oxazol-4-yl)pyrimidin-4-yl]amino]-3-[4-(dimethylcarbamoyloxy)phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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