CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7477
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00380590 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrimidin-4-ylamino)benzoic Acid Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Dihydrofolate reductase inhibitor 10-Oxaaminopterin family 1 2
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-... 13 1
Survival motor neuron protein inhibitor CHEMBL1307497 family 1 2
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Proto-oncogene tyrosine-protein kinase Src and Epidermal growt... 9 9
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 4 40
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(dime... 2 2
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-di... 14 8
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Epidermal growth factor receptor ligand SureCN4454332 family 18 5
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Renin and Cytochrome P450 3A4 inhibitor AGN-PC-046RG9 family 8 28
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 1 0
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(4-methoxyphenyl)... 2 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 12
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 3 1
Acyl-CoA desaturase inhibitor SureCN1182546 family 2 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[3,4-di... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380587 CHEMBL1684974 Bioactive SureCN2058946
CFAMM00380585 CHEMBL1684979 Bioactive SureCN2058588
CFAMM00380591 CHEMBL1684981 Bioactive SureCN2059200
CFAMM00380584 CHEMBL1684971 Bioactive (2S)-2-[[2-[cyclohexyl(methyl)amino]quinazolin-4-yl]amino]-3-[4-(dimethylcarbamoyloxy)phenyl]propanoic acid
CFAMM00380590 CHEMBL1684980 Bioactive SureCN2059024
CFAMM00380588 CHEMBL1684976 Bioactive SureCN2058948

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27273 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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