CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7485
Family Name Corticotropin-releasing factor receptor 1 ligand N-butyl-9-(2-chloro-4,6-dimethoxyphenyl)-N-ethyl-2,8-dimethylpurin-6-amine family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00380661 Functional Category Bioactive
Superfamily D(4) dopamine receptor and D(2) dopamine receptor Binder Superfamily
Class Class 3054

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 ligand AGN-PC-01ZUJG... 2 5
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00PFOP... 2 9
Corticotropin-releasing factor receptor 1 ligand AGN-PC-068CC4... 20 7
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Corticotropin-releasing factor receptor 1 ligand 2-N-(2-bromo-... 2 5
Corticotropin-releasing factor receptor 1 ligand SureCN7680546... 1 1
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 11 13
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Insulin-like growth factor 1 receptor and Potassium voltage-ga... 2 2
Corticotropin-releasing factor receptor 1 ligand 5-N-(2-chloro... 7 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00G4OY... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Receptor tyrosine-protein kinase erbB-2 ligand 2-[2-[4-[3-chlo... 4 5
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4,... 2 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-04UXCI... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380658 CHEMBL355721 Bioactive N-butyl-9-(2-chloro-4,6-dimethoxyphenyl)-N-ethyl-2-methylpurin-6-amine
CFAMM00380663 CHEMBL352378 Bioactive 2-N-(2-chloro-4,6-dimethoxyphenyl)-2-N,4-N,4-N-triethyl-6-methylpyrimidine-2,4-diamine
CFAMM00380662 CHEMBL168676 Bioactive N-butyl-3-(2-chloro-4,6-dimethoxyphenyl)-N-ethyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
CFAMM00380661 CHEMBL423444 Bioactive N-butyl-9-(2-chloro-4,6-dimethoxyphenyl)-N-ethyl-2,8-dimethylpurin-6-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543