CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7490
Family Name C-C chemokine receptor type 5 ligand SureCN3684128 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00380711 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 Ligand Vicriviroc Superfamily
Class Class 824

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
C-C chemokine receptor type 5 Ligand Vicriviroc Family 4 31
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
RAC-gamma serine/threonine-protein kinase Inhibitor GDC-0068 F... 20 29
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
C-C chemokine receptor type 5 ligand [3-[2-[(3aS,6aR)-5-(4,6-d... 3 40
C-C chemokine receptor type 5 ligand AC1NUXE1 family 12 7
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17d ... 5 9
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
C-C chemokine receptor type 5 ligand 6-chloro-N-[(3R)-3-[4-[(5... 16 4
C-C chemokine receptor type 5 ligand N-[3-[4-[3-cyclohexyl-5-(... 5 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 2
Cathepsin S and Cathepsin K inhibitor 2-cyano-N-[(2R)-1-phenyl... 2 0
C-C chemokine receptor type 5 ligand AC1MHPAK family 5 1


External ID

Functional Category

Molecule Name

CFAMM00380711 CHEMBL1688239 Bioactive SureCN3684128
CFAMM00380710 CHEMBL2435891 Bioactive N-[3-[4-[5-(3-bromophenyl)-3-cyclohexyl-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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