CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7497
Family Name Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-protein kinase receptor Ret ligand SureCN3003615 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00231652 Functional Category Bioactive
Superfamily Smoothened homolog Inhibitor LDE225 Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LDE225 Family 3 76
MK-6096 family 3 69
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380763 CHEMBL1688872 Bioactive AGN-PC-093OW6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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