CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7512
Family Name Corticotropin-releasing factor receptor 1 ligand N-butyl-N-ethyl-5-methyl-3-(2-methylsulfanyl-4-propan-2-ylphenyl)triazolo[4,5-b]pyridin-7-amine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00380857 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Ligand CRA1000 Superfamily
Class Class 1493

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
Corticotropin-releasing factor receptor 1 Ligand CRA1000 Family 4 39
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 14 4
5-hydroxytryptamine receptor 6 ligand AGN-PC-03P3TZ family 6 88
Corticotropin-releasing factor receptor 1 ligand SureCN6301726... 4 1
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 2
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 11 1


External ID

Functional Category

Molecule Name

CFAMM00380855 CHEMBL352353 Bioactive N,N-bis(2-methoxyethyl)-5-methyl-3-(2-methylsulfanyl-4-propan-2-ylphenyl)triazolo[4,5-b]pyridin-7-amine
CFAMM00380857 CHEMBL169010 Bioactive N-butyl-N-ethyl-5-methyl-3-(2-methylsulfanyl-4-propan-2-ylphenyl)triazolo[4,5-b]pyridin-7-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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