CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7517
Family Name Gonadotropin-releasing hormone receptor and Cytochrome P450 3A4 ligand 1-(7-azabicyclo[2.2.1]heptan-7-yl)-2-[3-[(2S)-1-[2-(1,3-benzoxazol-6-yl)ethylamino]propan-2-yl]-2-(3,5-dimethylphenyl)-1H-indol-5-yl]-2-methylpropan-1-one family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00234533 Functional Category Bioactive
Superfamily Cytochrome P450 3A4 and Beta-lactamase Binder Superfamily
Class Class 647

Cousin Family NamesSeedsMembers
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 4 0
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 2 0
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 3 1
Gonadotropin-releasing hormone receptor ligand methyl 4-[2-[[(... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380879 CHEMBL353395 Bioactive 1-(3-azabicyclo[2.2.2]octan-3-yl)-2-[3-[(2S)-1-[2-(1,3-benzoxazol-6-yl)ethylamino]propan-2-yl]-2-(3,5-dimethylphenyl)-1H-indol-5-yl]-2-methylpropan-1-one
CFAMM00380878 CHEMBL169238 Bioactive 1-(7-azabicyclo[2.2.1]heptan-7-yl)-2-[3-[(2S)-1-[2-(1,3-benzoxazol-5-yl)ethylamino]propan-2-yl]-2-(3,5-dimethylphenyl)-1H-indol-5-yl]-2-methylpropan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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