CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7530
Family Name Proto-oncogene tyrosine-protein kinase Src and Vascular endothelial growth factor receptor 2 ligand Benzofuran deriv. 11 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00380960 Functional Category Bioactive
Superfamily Ephrin type-B receptor 4 and Serine/threonine-protein kinase B-raf Binder Superfamily
Class Class 2579

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 25 40
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Proto-oncogene tyrosine-protein kinase Src inhibitor N-(2,4-di... 3 0
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075FPC ... 6 1
Tubulin beta-4A chain and Tubulin beta-2B chain inhibitor N-(2... 1 4
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00380962 CHEMBL352977 Bioactive AC1NS8IW
CFAMM00380961 CHEMBL172518 Bioactive Benzofuran deriv. 13
CFAMM00380960 CHEMBL169643 Bioactive Benzofuran deriv. 11

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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