CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7545
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-cyclohexylsulfonylcyclopentanecarbonyl)amino]-3-(4-phenylphenyl)propanoic acid family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00381133 Functional Category Bioactive
Superfamily Renin and Pol polyprotein Binder Superfamily
Class Class 168

Cousin Family NamesSeedsMembers
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Renin Inhibitor CP-80794 Family 16 112
Neprilysin Inhibitor Thiorphan Family 41 68
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-154957 Family 2 3
Endothelin-converting enzyme 1 Inhibitor PO3 2-leu-nal-o-3k Fa... 3 26
Genome polyprotein Inhibitor Acasp-glu-dif-glu-cha-cys Family 13 17
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Pol polyprotein inhibitor 169168-45-0 family 7 11
Neprilysin inhibitor SureCN489232 family 3 9
Pol polyprotein inhibitor Sulfone deriv. 31 family 15 4
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 3 3
Beta-secretase 1 and Cathepsin B inhibitor SureCN4666465 family 9 4
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2S,4R)... 5 8
Cathepsin E and Renin inhibitor (2S)-N-[2-[[(2S,3S,5S)-1-cyclo... 4 0
Beta-secretase 1 and Cathepsin B inhibitor 3-chloro-N-[(2S)-1-... 2 0
Renin inhibitor (1R,2R,3S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl... 5 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2S)-2-... 2 5
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Pol polyprotein inhibitor AC1LACBC family 2 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 2
Neprilysin inhibitor AGN-PC-02K4O6 family 2 0
Neprilysin inhibitor methyl (2S)-4-methyl-2-[[2-(sulfanylmethy... 3 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381133 CHEMBL170198 Bioactive (2S)-2-[(1-cyclohexylsulfonylcyclopentanecarbonyl)amino]-3-(4-phenylphenyl)propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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