CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7553
Family Name Platelet-activating factor receptor ligand SureCN7491834 family
No. of Seeds 28 No. of Other Members 15
Family Centroid CFAMM00381201 Functional Category Bioactive
Superfamily Platelet-activating factor receptor Binder Superfamily 2
Class Class 899

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
IPI-145 family 2 4
CC-486 family 7 103
Eluxadoline family 4 85
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 4
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 11
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Insulin-like growth factor 1 receptor ligand AGN-PC-09QGLU family 3 1
Platelet-activating factor receptor ligand SureCN7497229 family 4 2
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801305 ... 2 0
Mitogen-activated protein kinase 9 and MAP kinase-activated pr... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 3
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... 10 4
Mitogen-activated protein kinase 14 inhibitor methyl 4-[5-(eth... 3 11
Heat shock protein HSP 90-beta inhibitor 1-(2-amino-4-methylqu... 1 2
Neuropeptide Y receptor type 5 ligand AGN-PC-07R6YQ family 7 7
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Type-1 angiotensin II receptor ligand 2-butyl-3-[[4-(2-carboxy... 1 7
Type-1 angiotensin II receptor ligand 2-propyl-3-[[4-[2-(2H-te... 3 0
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Mitogen-activated protein kinase 14 inhibitor ethyl 4-[5-[(3-f... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 3
Platelet-activating factor receptor ligand SureCN7494441 family 1 1
Platelet-activating factor receptor ligand SureCN7497807 family 1 1
Histamine H3 receptor ligand AGN-PC-075YVW family 1 2
Platelet-activating factor receptor ligand AGN-PC-00GDIY family 1 1
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,... 6 15
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
Vascular endothelial growth factor receptor 2 and Vascular end... 1 0
Neutrophil elastase inhibitor AGN-PC-076VCN family 3 25
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 9 5
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 1 3
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381200 CHEMBL368923 Bioactive SureCN7494772
CFAMM00381213 CHEMBL368162 Bioactive SureCN7494309
CFAMM00381193 CHEMBL174592 Bioactive SureCN7492121
CFAMM00381180 CHEMBL368185 Bioactive methyl 1-(dimethylcarbamoyl)-3-[4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]cyclohexanecarbonyl]indole-4-carboxylate
CFAMM00381219 CHEMBL425688 Bioactive SureCN7494234
CFAMM00381179 CHEMBL369233 Bioactive AGN-PC-075A6U
CFAMM00381218 CHEMBL173586 Bioactive SureCN7493304
CFAMM00381205 CHEMBL367393 Bioactive SureCN7497573
CFAMM00381198 CHEMBL174198 Bioactive SureCN7494151
CFAMM00381211 CHEMBL170398 Bioactive methyl 1-(dimethylcarbamoyl)-3-[4-[(2-methyl-4-oxo-5H-imidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]indole-4-carboxylate
CFAMM00381178 CHEMBL366998 Bioactive SureCN7497825
CFAMM00381191 CHEMBL369643 Bioactive SureCN7498218
CFAMM00381204 CHEMBL369578 Bioactive methyl 1-[2-(dimethylamino)-2-oxoethyl]-3-[4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]indole-4-carboxylate
CFAMM00381217 CHEMBL354819 Bioactive methyl 3-[4-[(4-chloro-2-methylimidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-1-(dimethylcarbamoyl)indole-4-carboxylate
CFAMM00381197 CHEMBL173304 Bioactive SureCN7494285
CFAMM00381210 CHEMBL367425 Bioactive SureCN7493124
CFAMM00381190 CHEMBL173157 Bioactive SureCN7498500
CFAMM00381203 CHEMBL368113 Bioactive SureCN7491916
CFAMM00381183 CHEMBL366508 Bioactive SureCN7500255
CFAMM00381209 CHEMBL367922 Bioactive methyl 1-(dimethylcarbamoyl)-3-[4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-6-(2-phenylethynyl)indole-4-carboxylate
CFAMM00381189 CHEMBL369395 Bioactive SureCN7496288
CFAMM00381215 CHEMBL172819 Bioactive SureCN9084306
CFAMM00381182 CHEMBL174479 Bioactive SureCN7499027
CFAMM00381188 CHEMBL174183 Bioactive SureCN7498992
CFAMM00381201 CHEMBL367085 Bioactive SureCN7491834
CFAMM00381181 CHEMBL174262 Bioactive SureCN7494393
CFAMM00381194 CHEMBL172859 Bioactive methyl 1-(dimethylcarbamoyl)-3-[2-[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenyl]acetyl]indole-4-carboxylate
CFAMM00381207 CHEMBL427307 Bioactive SureCN7493679

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26853 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543