CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7566
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-(benzenesulfonyl)cyclohexanecarbonyl]amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00379445 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-4 Binder Superfamily 8
Class Class 590

Cousin Family NamesSeedsMembers
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368456 f... 3 23
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 12 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6367561 f... 20 12
Neprilysin inhibitor SureCN389939 family 5 6
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686971 f... 19 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor AGN-PC-074GDW f... 9 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-ethy... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(3-benz... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(4S)-3... 3 24
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 9 2
Integrin beta-1 and Integrin alpha-4 inhibitor (4S)-4-[benzene... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 16 23
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2R)-3-[4-(2-me... 18 1
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686827 f... 7 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-2... 2 21
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 4 1
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5687185 f... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-1-(3,5-dic... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 1 0
Integrin alpha-4 and Integrin beta-7 inhibitor (2S)-2-[[[(2S)-... 2 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381292 CHEMBL69035 Bioactive AGN-PC-074G9H
CFAMM00381290 CHEMBL171139 Bioactive (2S)-2-[[4-(benzenesulfonyl)thiane-4-carbonyl]amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid
CFAMM00381286 CHEMBL355536 Bioactive (2S)-2-[[1-(benzenesulfonyl)cyclobutanecarbonyl]amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27276 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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