CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7567
Family Name Neutrophil elastase inhibitor benzyl N-[(2S)-3-methyl-1-[(2S)-2-[[(2S)-3-methyl-1-[(4S)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxobutan-2-yl]carbamate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00381294 Functional Category Bioactive
Superfamily Neutrophil elastase and Prolyl endopeptidase Binder Superfamily
Class Class 1181

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cruzipain Inhibitor WRR-204 Family 18 35
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-lle-agly-ile-v... 17 7
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Cathepsin B and Cathepsin S Inhibitor Cbz-ile-leu-ala-leuvsme ... 12 14
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(1-me... 3 8
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 10 4
Prolyl endopeptidase and Chymotrypsin-like elastase family mem... 3 9
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Caspase-1 inhibitor (3S)-5-(3,3-diphenylpropanoyloxy)-3-[[(2S)... 3 6
Cathepsin S inhibitor SureCN7397817 family 9 4
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Pol polyprotein inhibitor AC1LADQG family 7 1
Neutrophil elastase inhibitor 1-O-benzyl 4-O-ethyl (3aS,6R,6aR... 3 4
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 0
Neutrophil elastase inhibitor 4-[(E)-3-[[(2S)-3-methyl-1-oxo-1... 2 6
Beta-lactamase inhibitor SureCN7195773 family 1 0
pyrrolidine-1,2-dicarboxylate NP ZINC04028685 Family 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381294 CHEMBL171288 Bioactive benzyl N-[(2S)-3-methyl-1-[(2S)-2-[[(2S)-3-methyl-1-[(4S)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxobutan-2-yl]carbamate
CFAMM00381293 CHEMBL354832 Bioactive benzyl N-[(2S)-1-[(2S)-2-[[(2S)-1-(4,5-dihydro-1,3-oxazol-2-yl)-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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