CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7569
Family Name Transporter and Sodium-dependent dopamine transporter inhibitor (10bS)-6-(3,4-dichlorophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00381295 Functional Category Bioactive
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-phenyl)-1-methyl-piperidine-2-thione Superfamily
Class Class 48

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Zicronapine family 43 62
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 3 7
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 6 7
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34
Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichloropheny... 2 10
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 5 6
Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 18 4
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 6 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 9 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand 2-[4... 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1
Sigma non-opioid intracellular receptor 1 ligand NCI60_039912 ... 2 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 2 1
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand 2-[2-[(... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand (NE)-N-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381295 CHEMBL171474 Bioactive (10bS)-6-(3,4-dichlorophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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