CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7574
Family Name Endothelin-1 receptor ligand SureCN8118632 family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00381315 Functional Category Bioactive with Natural Product
Superfamily Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 10
Class Class 2015

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Hemoglobin subunit alpha Inhibitor 4-[(5-methoxy-2-methylpheno... 3 12
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAF proto-oncogene serine/threonine-protein kinase Inhibitor 5... 3 7
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Renin Inhibitor CP-305202 Family 9 30
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Leukotriene B4 receptor 1 ligand AGN-PC-04XM3V family 3 10
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Cellular tumor antigen p53 and Lethal(3)malignant brain tumor-... 1 6
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 1 18
Thromboxane A2 receptor and Thromboxane-A synthase ligand Ici ... 3 17
Prostaglandin D2 receptor 2 ligand SureCN137822 family 3 0
Retinoic acid receptor RXR-alpha ligand 6-[(3-butoxy-5,5,8,8-t... 2 2
Proteinase-activated receptor 1 ligand (3R,3aR,4S,5R,6S,7aS)-5... 2 3
Xanthine dehydrogenase/oxidase inhibitor 4-[[4-(2-aminopyrimid... 3 16
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Thromboxane-A synthase inhibitor (E)-7-[4-[5-[(2S,4S,5R)-5-[(Z... 3 9
Thromboxane-A synthase inhibitor SureCN9045578 family 1 12
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 1 7
Bile acid receptor ligand pyridin-4-yl (1R,3aS,5aR,5bR,7aR,9S,... 1 0
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 1 0
Aromatase inhibitor (4-chlorophenyl)-(6-methoxy-1-benzofuran-2... 1 4
Arachidonate 5-lipoxygenase inhibitor 4-(furan-3-yl)-7-[[5-(4-... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381317 CHEMBL2110232 Bioactive SureCN8118089
CFAMM00381308 CHEMBL329181 Bioactive SureCN7907755
CFAMM00381315 CHEMBL174092 Bioactive SureCN8118632
CFAMM00381310 CHEMBL171844 Bioactive SureCN8128630

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26823 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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