CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7577
Family Name Tryptase alpha/beta-1 inhibitor methyl 3-[3-(aminomethyl)phenyl]-2-[3-[[2-[(2S,5R)-5-[2-[[3-[[3-[3-(aminomethyl)phenyl]-1-methoxy-1-oxopropan-2-yl]amino]-3-oxopropyl]amino]-2-oxoethyl]-3,6-dioxopiperazin-2-yl]acetyl]amino]propanoylamino]propanoate family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00381332 Functional Category Bioactive
Superfamily Cholinesterase and Acetylcholinesterase Binder Superfamily 9
Class Class 506

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Dopamine reuptake Inhibitor Amineptine Family 2 5
Neuromedin-K receptor Ligand Senktide Family 15 22
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Genome polyprotein Inhibitor Acasp-glu-dif-glu-cha-cys Family 13 17
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Renin and Cathepsin D inhibitor (3S)-4-[[6-acetamido-2-[[3-nap... 6 26
Growth factor receptor-bound protein 2 ligand 2-[(9S,10S,11E,1... 5 14
Growth factor receptor-bound protein 2 ligand [4-[[(2S,5S,9S,1... 2 1
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Growth hormone-releasing hormone receptor ligand (1S)-1'-[(2R)... 7 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 6
Ribonucleoside-diphosphate reductase large subunit and Ribonuc... 1 0
Gamma-secretase subunit PEN-2 inhibitor SureCN5966881 family 1 9
Beta-secretase 1 inhibitor (2R)-4-amino-2-[[(2S)-2-[[(2S)-2-[[... 2 1
Pol polyprotein inhibitor methyl (2S)-2-[[(2S)-2-[[(2S)-2-[5-[... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381332 CHEMBL171905 Bioactive methyl 3-[3-(aminomethyl)phenyl]-2-[3-[[2-[(2S,5R)-5-[2-[[3-[[3-[3-(aminomethyl)phenyl]-1-methoxy-1-oxopropan-2-yl]amino]-3-oxopropyl]amino]-2-oxoethyl]-3,6-dioxopiperazin-2-yl]acetyl]amino]propanoylamino]propanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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