CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7578
Family Name Pol polyprotein inhibitor arylsulfonamide 10c family
No. of Seeds 17 No. of Other Members 2
Family Centroid CFAMM00381344 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 25
Class Class 3387

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Pol polyprotein inhibitor AC1LA6RA family 4 12
Pol polyprotein inhibitor AC1NQUJL family 10 11
Pol polyprotein inhibitor AC1O41ZS family 2 0


External ID

Functional Category

Molecule Name

CFAMM00381338 CHEMBL422718 Bioactive AC1LAPOO
CFAMM00381351 CHEMBL362787 Bioactive AC1O41ZM
CFAMM00381344 CHEMBL177470 Bioactive arylsulfonamide 10c
CFAMM00381350 CHEMBL355306 Bioactive arylsulfonamide 16b
CFAMM00381337 CHEMBL190372 Bioactive AC1O41ZU
CFAMM00381343 CHEMBL171947 Bioactive arylsulfonamide 15
CFAMM00381336 CHEMBL362312 Bioactive N-alkoxysulfonamide analog 23
CFAMM00381349 CHEMBL353288 Bioactive arylsulfonamide 16a
CFAMM00381342 CHEMBL368496 Bioactive arylsulfonamide 13
CFAMM00381335 CHEMBL469086 Bioactive TMC 126
CFAMM00381348 CHEMBL174779 Bioactive arylsulfonamide 11c
CFAMM00381341 CHEMBL264818 Bioactive [(4S)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[cyclopentyloxy-(4-methoxyphenyl)sulfonylamino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
CFAMM00381334 CHEMBL364424 Bioactive N-alkoxysulfonamide analog 22
CFAMM00381340 CHEMBL302859 Bioactive [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[3-hydroxy-4-[(4-methoxyphenyl)sulfonyl-(2-methylpropyl)amino]-1-phenylbutan-2-yl]carbamate
CFAMM00381333 CHEMBL439853 Bioactive AC1O41ZW
CFAMM00381339 CHEMBL433973 Bioactive arylsulfonamide 20
CFAMM00381345 CHEMBL367454 Bioactive arylsulfonamide 16c

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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