CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7580
Family Name Pol polyprotein inhibitor KNI-1279 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00381423 Functional Category Bioactive
Superfamily Pol polyprotein and Cathepsin S Binder Superfamily
Class Class 322

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Nelfinavir Family 11 26
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Pol polyprotein inhibitor CHEMBL305466 family 4 7
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Beta-secretase 1 and Cathepsin E inhibitor 1-N-[(1R,2S)-3-(3,5... 3 8
Pol polyprotein inhibitor AC1LA3AI family 5 9
Pol polyprotein inhibitor 168912-67-2 family 1 0
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7
Renin inhibitor N-[(2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381425 CHEMBL176930 Bioactive KNI-1166
CFAMM00381424 CHEMBL367679 Bioactive KNI-1277
CFAMM00381423 CHEMBL172012 Bioactive KNI-1279

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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