CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7586
Family Name Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00381448 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and D(2) dopamine receptor Binder Superfamily
Class Class 2912

Cousin Family NamesSeedsMembers
Histone deacetylase Inhibitor Abexinostat Family 1 20
Histamine H3 receptor Ligand A-317920 Family 9 240
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Histamine H3 receptor Ligand A-349821 Family 49 228
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Fatty-acid amide hydrolase 1 Inhibitor Furan-2-ylmethylcarbami... 1 105
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-... 2 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 4
Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-074X... 5 6
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(benze... 3 14
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 14
Sodium/iodide cotransporter inhibitor (3-methoxyphenyl)methyl ... 4 12
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1424193 family 1 0
Peptide deformylase inhibitor (2R)-N-[(2S)-1-(1-benzofuran-2-y... 3 1
Mu-type opioid receptor ligand SureCN9379472 family 1 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Collagenase 3 and Matrilysin inhibitor N-({4'-[(1-BENZOFURAN-2... 24 45
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 3
Histamine H3 receptor ligand SureCN5221194 family 1 8
Histamine H3 receptor ligand SureCN5218144 family 4 6
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 4 13
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 1
Glutamate carboxypeptidase 2 inhibitor (2S)-2-[[(1S)-1-carboxy... 1 0
Gonadotropin-releasing hormone receptor ligand N-[[4-[(diamino... 6 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00AWDS ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381450 CHEMBL172262 Bioactive SureCN10975992
CFAMM00381448 CHEMBL190185 Bioactive SureCN5653729
CFAMM00381447 CHEMBL192729 Bioactive SureCN5653172

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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