CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7604
Family Name Matrix metalloproteinase-9 inhibitor (3R)-2-[ethoxy-(4-phenylphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamide family
No. of Seeds 4 No. of Other Members 15
Family Centroid CFAMM00381579 Functional Category Bioactive
Superfamily Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 Superfamily
Class Class 1787

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 F... 3 51
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Neprilysin and Aminopeptidase N inhibitor (2S)-2-[[(2S)-2-[[[a... 13 1
Neprilysin inhibitor SureCN489232 family 3 9
Neutrophil collagenase and Collagenase 3 inhibitor n-[[2-methy... 1 4
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Collagenase 3 and Interstitial collagenase inhibitor (4-benzyl... 2 0
Endothelin-converting enzyme 1 and Neprilysin inhibitor [[(2S)... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381575 CHEMBL539171 Bioactive AGN-PC-0759HA
CFAMM00381574 CHEMBL172885 Bioactive 2-[ethoxy-(4-fluorophenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamide
CFAMM00381573 CHEMBL172886 Bioactive AGN-PC-0759DB
CFAMM00381579 CHEMBL372702 Bioactive (3R)-2-[ethoxy-(4-phenylphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26820 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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