CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7605
Family Name Caspase-1 inhibitor AGN-PC-075AEI family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00381591 Functional Category Bioactive
Superfamily Kappa-type opioid receptor and Delta-type opioid receptor Binder Superfamily 6
Class Class 884

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor L-709780 Family 9 10
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Angiotensin-converting enzyme inhibitor (S)-1-((S)-5-benzamido... 5 2
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7285564... 1 2
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 1
Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-7-benzamido-N-[... 7 18
Caspase-1 and Caspase-8 inhibitor N-[(6S)-3-(benzamidomethyl)-... 4 4
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN6949669... 12 3
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381592 CHEMBL172900 Bioactive AGN-PC-0759MT
CFAMM00381591 CHEMBL177364 Bioactive AGN-PC-075AEI
CFAMM00381593 CHEMBL424953 Bioactive AGN-PC-075AEH

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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