CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7615
Family Name Substance-K receptor ligand AGN-PC-0759BS family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00381664 Functional Category Bioactive
Superfamily Substance-K receptor and Substance-P receptor Binder Superfamily 6
Class Class 4490

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Haloperidol Family 5 53
Delta-type opioid receptor Ligand Loperamide Family 8 55
Neuromedin-K receptor Ligand Osanetant Family 38 192
Sodium-dependent serotonin transporter and Transporter inhibit... 6 9
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 9 0
Substance-K receptor ligand SureCN8118421 family 4 1
Renin and Potassium voltage-gated channel subfamily H member 2... 3 0
C-C chemokine receptor type 1 ligand 4-chloro-N-[(2R)-1-[(4S)-... 6 3
Substance-P receptor and Substance-K receptor ligand N-[(2Z)-3... 5 0
Substance-K receptor ligand N-[2-(3,4-dichlorophenyl)-4-(4-hyd... 1 0


External ID

Functional Category

Molecule Name

CFAMM00381665 CHEMBL173203 Bioactive AGN-PC-0758WZ
CFAMM00381671 CHEMBL176853 Bioactive N-[2-(3,4-dichlorophenyl)-4-(4-hydroxy-4-phenylpiperidin-1-yl)butyl]-N-methylnaphthalene-1-carboxamide
CFAMM00381664 CHEMBL173841 Bioactive AGN-PC-0759BS

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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