CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7618
Family Name Pol polyprotein inhibitor N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxopentan-2-yl]carbamoyl]-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]benzamide family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00381686 Functional Category Bioactive
Superfamily NS5B protein and Beta-lactamase Binder Superfamily
Class Class 681

Cousin Family NamesSeedsMembers
Renin Inhibitor Enalkiren Family 56 44
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Pol polyprotein inhibitor penicillin deriv. 71 family 1 2
Pol polyprotein and Protease inhibitor 161186-52-3 family 3 3
Pol polyprotein inhibitor AC1LAQE0 family 13 4
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Pol polyprotein inhibitor (2S)-4-(1H-benzimidazol-2-ylmethyl)-... 1 0
Pol polyprotein and Renin inhibitor U-75875 family 12 1
Pol polyprotein inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-... 7 3
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 2 8
Pol polyprotein and Protease inhibitor 161186-51-2 family 5 0
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[4-[4-[(... 9 7
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Pol polyprotein inhibitor AC1LAQDX family 3 0
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381687 CHEMBL173255 Bioactive N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxopentan-2-yl]carbamoyl]-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-(phenylsulfanylmethoxy)benzamide
CFAMM00381686 CHEMBL175393 Bioactive N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxopentan-2-yl]carbamoyl]-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]benzamide
CFAMM00381684 CHEMBL366392 Bioactive AC1LA9MA
CFAMM00381689 CHEMBL176353 Bioactive AC1LA9DI
CFAMM00381688 CHEMBL428804 Bioactive AC1NUJK0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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