CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor SureCN3218019 family
No. of Seeds 20 No. of Other Members 28
Family Centroid CFAMM00315090 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Binder Superfamily 2
Class Class 1256

Cousin Family NamesSeedsMembers
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Coagulation factor X and Prothrombin Inhibitor BMS-344577 Family 13 12
Potassium voltage-gated channel subfamily H member 2 and Neuro... 3 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 9 3
Thromboxane A2 receptor ligand AC1NSKJR family 13 42
Aldo-keto reductase family 1 member B10 and Aldose reductase i... 4 13
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 4 0
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 14 6
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Serine/threonine-protein kinase pim-1 inhibitor (2Z)-6-methoxy... 1 5
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Aromatase inhibitor (4-chlorophenyl)-(6-methoxy-1-benzofuran-2... 1 4
Tyrosine-protein kinase Lck and Angiopoietin-1 receptor ligand... 1 0


External ID

Functional Category

Molecule Name

CFAMM00315064 CHEMBL1092486 Bioactive SureCN4385856
CFAMM00315077 CHEMBL1091456 Bioactive SureCN3228206
CFAMM00315090 CHEMBL1091491 Bioactive SureCN3218019
CFAMM00315063 CHEMBL1092485 Bioactive SureCN4382374
CFAMM00315076 CHEMBL1092119 Bioactive SureCN3223853
CFAMM00315055 CHEMBL1088745 Bioactive SureCN4394989
CFAMM00315082 CHEMBL1090382 Bioactive SureCN4387554
CFAMM00315088 CHEMBL1091492 Bioactive SureCN4280289
CFAMM00315081 CHEMBL1090383 Bioactive SureCN4385753
CFAMM00315095 CHEMBL1094017 Bioactive SureCN4380560
CFAMM00315061 CHEMBL1092768 Bioactive SureCN4388159
CFAMM00315074 CHEMBL1092781 Bioactive SureCN4385088
CFAMM00315094 CHEMBL1094015 Bioactive SureCN4388247
CFAMM00315073 CHEMBL1090043 Bioactive SureCN4390040
CFAMM00315086 CHEMBL1090388 Bioactive SureCN4386066
CFAMM00315066 CHEMBL1092815 Bioactive SureCN3221714
CFAMM00315079 CHEMBL1090381 Bioactive SureCN3215195
CFAMM00315085 CHEMBL1093754 Bioactive SureCN4388632
CFAMM00315051 CHEMBL1092120 Bioactive SureCN3227381
CFAMM00315091 CHEMBL1092754 Bioactive SureCN4385411

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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