CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7625
Family Name Beta-3 adrenergic receptor ligand N-[5-[2-[[1-[4-[(Z)-(2-amino-4-oxo-1,3-thiazol-5-ylidene)methyl]phenyl]piperidin-4-yl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00381732 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-1 adrenergic receptor Binder Superfamily
Class Class 880

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Formoterol Family 16 63
Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
Beta-3 adrenergic receptor Ligand BMS-196085 Family 18 72
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 5 16
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 5
Beta-2 adrenergic receptor ligand SureCN5041910 family 12 1
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0


External ID

Functional Category

Molecule Name

CFAMM00381730 CHEMBL177400 Bioactive 2-[(5Z)-5-[[4-[4-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(methanesulfonamido)phenyl]ethyl]amino]piperidin-1-yl]phenyl]methylidene]-4-oxo-1,3-thiazol-2-yl]-1,1-dimethylguanidine
CFAMM00381734 CHEMBL366657 Bioactive N-[5-[(1R)-2-[[1-[4-[(Z)-[2-(cyanoamino)-4-oxo-1,3-thiazol-5-ylidene]methyl]phenyl]piperidin-4-yl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00381733 CHEMBL177185 Bioactive N-[5-[2-[[1-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]piperidin-4-yl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00381732 CHEMBL173472 Bioactive N-[5-[2-[[1-[4-[(Z)-(2-amino-4-oxo-1,3-thiazol-5-ylidene)methyl]phenyl]piperidin-4-yl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00381731 CHEMBL174442 Bioactive N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[1-[4-[(Z)-(4-oxo-2-piperidin-1-yl-1,3-thiazol-5-ylidene)methyl]phenyl]piperidin-4-yl]amino]ethyl]phenyl]methanesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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