CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7627
Family Name Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene receptor 1 ligand AGN-PC-03OZTS family
No. of Seeds 16 No. of Other Members 5
Family Centroid CFAMM00381746 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031 Superfamily
Class Class 866

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Leukotriene B4 receptor 1 Ligand SB-201993 Family 5 13
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phe... 2 2
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Cysteinyl leukotriene receptor 1 ligand 4-[(2S)-2-[[7-(quinoli... 6 15
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Cysteinyl leukotriene receptor 1 ligand SureCN9053715 family 2 11
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Transient receptor potential cation channel subfamily V member... 54 12
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 3 5
Disintegrin and metalloproteinase domain-containing protein 17... 8 0
Mu-type opioid receptor ligand MITRAGYNINE family 2 8
Prothrombin and Trypsin-1 inhibitor AGN-PC-074I4I family 3 1
Disintegrin and metalloproteinase domain-containing protein 17... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[(1-acetylpiperidin-4... 58 15
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 0
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-[2-[2-(dimethylamino)et... 2 0
NS3 and Non-structural protein 4A inhibitor 4-[2-[[(2S)-2-[[(2... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381746 CHEMBL175382 Bioactive AGN-PC-03OZTS
CFAMM00381739 CHEMBL176654 Bioactive AGN-PC-03OZU7
CFAMM00381752 CHEMBL176961 Bioactive AGN-PC-03OZTO
CFAMM00381751 CHEMBL368666 Bioactive AGN-PC-03OZT1
CFAMM00381738 CHEMBL367424 Bioactive SureCN8180186
CFAMM00381757 CHEMBL178221 Bioactive CGP-57698
CFAMM00381737 CHEMBL178049 Bioactive AGN-PC-03OZU4
CFAMM00381743 CHEMBL174575 Bioactive AGN-PC-03OZTJ
CFAMM00381749 CHEMBL175419 Bioactive AGN-PC-03OZUC
CFAMM00381742 CHEMBL174687 Bioactive AGN-PC-075AAX
CFAMM00381755 CHEMBL369421 Bioactive AGN-PC-03OZUV
CFAMM00381748 CHEMBL173523 Bioactive AGN-PC-03OZU1
CFAMM00381741 CHEMBL368290 Bioactive AGN-PC-075A7I
CFAMM00381754 CHEMBL362228 Bioactive AGN-PC-03OZUZ
CFAMM00381747 CHEMBL174265 Bioactive AGN-PC-03OZT3
CFAMM00381740 CHEMBL177814 Bioactive AGN-PC-03OZT6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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