CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM764
Family Name Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[1-[(2,4-dichlorophenyl)methyl]-2-oxo-3H-indol-7-yl]-N-(3,4-difluorophenyl)sulfonylprop-2-enamide family
No. of Seeds 20 No. of Other Members 3
Family Centroid CFAMM00315147 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and Prostaglandin E2 receptor EP3 subtype Binder Superfamily
Class Class 3220

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(4,5-dichlo... 4 9
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[1-(naphtha... 13 5
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-dichlo... 8 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[1-[(2,4-di... 8 2
Prostaglandin E2 receptor EP3 subtype and Prostaglandin F2-alp... 7 2
Prostaglandin E2 receptor EP3 subtype and Prostaglandin F2-alp... 5 1
Prostaglandin E2 receptor EP3 subtype and Prostaglandin F2-alp... 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00315148 CHEMBL1091892 Bioactive (E)-N-(3-chlorophenyl)sulfonyl-3-[1-[(3,4-difluorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]prop-2-enamide
CFAMM00315161 CHEMBL1091622 Bioactive (E)-N-(3,4-dichlorophenyl)sulfonyl-3-[1-[(3,4-difluorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]prop-2-enamide
CFAMM00315141 CHEMBL1090507 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-3-methyl-2-oxo-3H-indol-7-yl]-N-(3,4-dichlorophenyl)sulfonylprop-2-enamide
CFAMM00315147 CHEMBL1090113 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-2-oxo-3H-indol-7-yl]-N-(3,4-difluorophenyl)sulfonylprop-2-enamide
CFAMM00315160 CHEMBL1091606 Bioactive (E)-N-(4-chlorophenyl)sulfonyl-3-[1-[(2,4-dichlorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]prop-2-enamide
CFAMM00315140 CHEMBL1089094 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]-N-(3,4-dichlorophenyl)sulfonylprop-2-enamide
CFAMM00315153 CHEMBL1090112 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-2-oxo-3H-indol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00315146 CHEMBL1090501 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00315159 CHEMBL1093797 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-2-oxo-3H-indol-7-yl]-N-(3,4-dichlorophenyl)sulfonylprop-2-enamide
CFAMM00315145 CHEMBL1088780 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]-N-(3,4-difluorophenyl)sulfonylprop-2-enamide
CFAMM00315158 CHEMBL1089161 Bioactive (E)-N-(3-chlorophenyl)sulfonyl-3-[1-[(2,4-dichlorophenyl)methyl]-3-methyl-2-oxo-3H-indol-7-yl]prop-2-enamide
CFAMM00315151 CHEMBL1090498 Bioactive (E)-N-(3-chlorophenyl)sulfonyl-3-[1-[(3,4-difluorophenyl)methyl]-3-methyl-2-oxo-3H-indol-7-yl]prop-2-enamide
CFAMM00315144 CHEMBL1089491 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-3-methyl-2-oxo-3H-indol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00315150 CHEMBL1091164 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-3-methyl-2-oxo-3H-indol-7-yl]-N-(3,4-difluorophenyl)sulfonylprop-2-enamide
CFAMM00315156 CHEMBL1093124 Bioactive (E)-N-(3,4-dichlorophenyl)sulfonyl-3-[1-[(3,4-difluorophenyl)methyl]-3-methyl-2-oxo-3H-indol-7-yl]prop-2-enamide
CFAMM00315143 CHEMBL1092230 Bioactive (E)-N-(3-chlorophenyl)sulfonyl-3-[1-[(2,4-dichlorophenyl)methyl]-2-oxo-3H-indol-7-yl]prop-2-enamide
CFAMM00315149 CHEMBL1092871 Bioactive (E)-N-(3,4-dichlorophenyl)sulfonyl-3-[1-[(3,4-difluorophenyl)methyl]-2-oxo-3H-indol-7-yl]prop-2-enamide
CFAMM00315162 CHEMBL1089095 Bioactive (E)-N-(3-chlorophenyl)sulfonyl-3-[1-[(2,4-dichlorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]prop-2-enamide
CFAMM00315142 CHEMBL1093239 Bioactive (E)-3-[1-[(2,4-dichlorophenyl)methyl]-3,3-difluoro-2-oxoindol-7-yl]-N-(4-fluorophenyl)sulfonylprop-2-enamide
CFAMM00315155 CHEMBL1088848 Bioactive (E)-N-(3-chlorophenyl)sulfonyl-3-[1-[(3,4-difluorophenyl)methyl]-2-oxo-3H-indol-7-yl]prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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