CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7641
Family Name Adenosine receptor A2a ligand 5-N-[[(2R)-1-[(2-chloro-3,6-difluorophenyl)methyl]pyrrolidin-2-yl]methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine family
No. of Seeds 7 No. of Other Members 9
Family Centroid CFAMM00381923 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 1 Ligand PF-1913539 Superfamily
Class Class 1038

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
Adenosine receptor A1 and Adenosine receptor A2a Ligand ZM-241... 2 5
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 1
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 11 0
Adenosine receptor A2a ligand SureCN6867940 family 13 13
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 8 0
Prelamin-A/C and Prothrombin inhibitor (3-Furan-2-yl-5-methyls... 2 1
Adenosine receptor A3 and Adenosine receptor A2b ligand CHEMBL... 5 0
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 5 8
Adenosine receptor A2a ligand 5-[[[(2R)-1-[(2-chloropyridin-4-... 5 0
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Adenosine receptor A2a ligand 7-(3,4-dimethoxyphenyl)-2-(furan... 6 1
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 5
Adenosine receptor A3 ligand CHEMBL1834703 family 2 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 6
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 0
Adenosine receptor A2a and Adenosine receptor A1 ligand 5-[(7S... 6 1
Adenosine receptor A2a ligand 5-[(7S,9aS)-7-[(2-fluorophenoxy)... 5 4
P2X purinoceptor 7 inhibitor SureCN110566 family 1 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 3
Adenosine receptor A2a ligand 3-[(2-bromophenyl)methyl]-8-(fur... 2 0
Adenosine receptor A2a ligand 8-(furan-2-yl)-3-[2-[4-(1,3-thia... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 25 5
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 29 1
Adenosine receptor A2a and Adenosine receptor A1 ligand 1-[(2-... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Adenosine receptor A2a ligand SureCN8368237 family 1 0
Adenosine receptor A2a ligand AGN-PC-02Z2S3 family 3 0
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 19 2
Adenosine receptor A2a and Adenosine receptor A1 ligand triazi... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381909 CHEMBL367593 Bioactive 5-N-[[(2R)-1-[[3-chloro-2-fluoro-6-(trifluoromethyl)phenyl]methyl]pyrrolidin-2-yl]methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
CFAMM00381915 CHEMBL173993 Bioactive 5-N-[[(2R)-1-[(3-chloro-2-fluorophenyl)methyl]pyrrolidin-2-yl]methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
CFAMM00381921 CHEMBL368201 Bioactive 5-N-[[(2R)-1-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]pyrrolidin-2-yl]methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
CFAMM00381913 CHEMBL179478 Bioactive 5-N-[[(2R)-1-[(5-chlorofuran-2-yl)methyl]pyrrolidin-2-yl]methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
CFAMM00381910 CHEMBL176071 Bioactive 5-N-[[(2R)-1-[[2-fluoro-5-(trifluoromethyl)phenyl]methyl]pyrrolidin-2-yl]methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
CFAMM00381923 CHEMBL177615 Bioactive 5-N-[[(2R)-1-[(2-chloro-3,6-difluorophenyl)methyl]pyrrolidin-2-yl]methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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