CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7642
Family Name 5-hydroxytryptamine receptor 2A ligand SureCN5215979 family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00381925 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 Inhibitor Celecoxib Superfamily
Class Class 428

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Celecoxib Family 3 97
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Prostaglandin G/H synthase 1 Inhibitor 1-(4-aminosulfonylpheny... 3 18
Prostaglandin G/H synthase 2 Inhibitor SC-558 Family 1 2
Prostaglandin G/H synthase 2 Inhibitor 1-(4-(methylsulfonyl)ph... 1 2
Motilin receptor and Cytochrome P450 2D6 ligand 7-[[6-(4-chlor... 2 1
Glucocorticoid receptor ligand N-[(3S)-3-[1-(4-fluorophenyl)in... 11 24
5-hydroxytryptamine receptor 6 ligand AGN-PC-07ZA0N family 1 3
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 10 2
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
Cannabinoid receptor 2 ligand 1,1,1-trifluoro-N-[(2S)-6-(1-pyr... 2 1
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 8
Survival motor neuron protein and 15-hydroxyprostaglandin dehy... 1 35
5-hydroxytryptamine receptor 6 ligand AGN-PC-09QKIN family 2 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
5-hydroxytryptamine receptor 6 and Muscarinic acetylcholine re... 7 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
Prostaglandin G/H synthase 2 inhibitor 1-(3,4-difluorophenyl)-... 1 3
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 1
Carbonic anhydrase 2 and Carbonic anhydrase 12 inhibitor 5-[1-... 7 5
Glucocorticoid receptor ligand (4aR)-1-(4-fluorophenyl)-4a-(me... 18 2
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Glucocorticoid receptor ligand 4-[[(4aS)-6-(4-tert-butylphenyl... 4 0
Glucocorticoid receptor ligand 6-benzyl-1-(4-fluorophenyl)-4a-... 2 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-00EW0T family 2 7
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 3
Carbonic anhydrase 2 inhibitor 4-[1-[(2S)-1-(3-azabicyclo[3.2.... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 2 1
Prostaglandin D2 receptor 2 ligand SureCN2516080 family 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 4-(7-c... 1 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381929 CHEMBL178055 Bioactive SureCN5210749
CFAMM00381925 CHEMBL174049 Bioactive SureCN5215979

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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