CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7643
Family Name Platelet-activating factor receptor ligand SureCN7497229 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00381941 Functional Category Bioactive
Superfamily Platelet-activating factor receptor and Beta-lactamase Binder Superfamily
Class Class 1256

Cousin Family NamesSeedsMembers
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Divapl... 3 47
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 3
Disintegrin and metalloproteinase domain-containing protein 17... 4 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 3 8
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 5
Collagenase 3 inhibitor 1-[6-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 4 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 8 13
Substance-P receptor ligand N-[(2R)-1-[acetyl-[(2-chlorophenyl... 2 2
Insulin-like growth factor 1 receptor ligand 3-[8-amino-1-(4-e... 9 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
5-hydroxytryptamine receptor 6 ligand 2-[(2Z)-2-[3-[(3-methoxy... 1 11
Platelet-activating factor receptor ligand SureCN7494441 family 1 1
Platelet-activating factor receptor ligand SureCN7497807 family 1 1
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Platelet-activating factor receptor ligand AGN-PC-00GDIY family 1 1
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Histone deacetylase 1 inhibitor (7S)-N-hydroxy-7-[[2-(5-methox... 1 2
Gastrin/cholecystokinin type B receptor ligand AGN-PC-077L8M f... 24 10
Cholecystokinin receptor type A ligand AGN-PC-077L8J family 22 2
Cholecystokinin receptor type A ligand SureCN3132309 family 11 0
Cholecystokinin receptor type A ligand AGN-PC-077KXF family 2 0
Bromodomain-containing protein 4 and Bromodomain-containing pr... 3 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381941 CHEMBL369614 Bioactive SureCN7497229
CFAMM00381940 CHEMBL435115 Bioactive SureCN7496175
CFAMM00381938 CHEMBL367941 Bioactive SureCN7493565
CFAMM00381936 CHEMBL174104 Bioactive AGN-PC-00GF7V

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27433 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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