CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7645
Family Name Adenosine kinase inhibitor 7-[(4aS,7aS)-6-benzyl-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-1-yl]-2-phenyl-[1,3]oxazolo[5,4-d]pyrimidine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00381945 Functional Category Bioactive
Superfamily MK-3328 Superfamily
Class Class 681

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand BIIB014 Family 26 92
MK-3328 family 2 32
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Orexin receptor type 1 and Orexin receptor type 2 Ligand MK-43... 2 1
Histamine H4 receptor and Histamine H3 receptor ligand SureCN6... 17 51
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Histamine H4 receptor ligand 8-fluoro-4-[(3R)-3-(methylamino)p... 6 1
Histamine H4 receptor ligand 8-chloro-4-[(3R)-3-(methylamino)p... 1 1
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 1 0
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00381945 CHEMBL174158 Bioactive 7-[(4aS,7aS)-6-benzyl-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-1-yl]-2-phenyl-[1,3]oxazolo[5,4-d]pyrimidine
CFAMM00381943 CHEMBL360273 Bioactive 7-[(3aS,6aS)-1-benzyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-2-phenyl-[1,3]oxazolo[5,4-d]pyrimidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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