CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7658
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2A ligand (Z)-but-2-enedioic acid;1-[2-[4-[5-chloro-3-(2-fluorophenyl)-2,3-dihydro-1H-inden-1-yl]piperazin-1-yl]ethyl]-3-propan-2-ylimidazolidin-2-one family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00172194 Functional Category Bioactive
Superfamily Zicronapine Superfamily
Class Class 1324

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-P receptor Ligand Orvepitant Family 11 46
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131
Substance-P receptor Ligand Vestipitant Family 14 137
Zicronapine family 43 62
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
Sodium-dependent serotonin transporter Inhibitor Tefludazine F... 8 9
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 5 6
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
D(1A) dopamine receptor and 5-hydroxytryptamine receptor 2A li... 2 0
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 9 0
Neuromedin-K receptor ligand (1S,2R)-1-(3,4-dichlorophenyl)-N-... 8 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
D(1A) dopamine receptor and D(3) dopamine receptor ligand 2-[4... 1 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 2 1
Neuromedin-K receptor and Substance-K receptor ligand AGN-PC-0... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543