CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7661
Family Name Alpha-1D adrenergic receptor ligand (E)-but-2-enedioic acid;5-[1-(4-methylthiophen-3-yl)ethyl]-1H-imidazole family
No. of Seeds 8 No. of Other Members 1
Family Centroid CFAMM00382013 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor and Alpha-2A adrenergic receptor Binder Superfamily
Class Class 4575

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Alpha-1D adrenergic receptor ligand 5-[(3-bromothiophen-2-yl)m... 8 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 22
Alpha-1D adrenergic receptor ligand (E)-but-2-enedioic acid;5-... 1 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Histamine H3 receptor and Histamine H4 receptor ligand AGN-PC-... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382013 CHEMBL1744271 Bioactive (E)-but-2-enedioic acid;5-[1-(4-methylthiophen-3-yl)ethyl]-1H-imidazole
CFAMM00382012 CHEMBL1744291 Bioactive (E)-but-2-enedioic acid;5-[(4-methylthiophen-3-yl)methyl]-1H-imidazole
CFAMM00382018 CHEMBL1744287 Bioactive (E)-but-2-enedioic acid;5-[1-(4-methylthiophen-3-yl)propyl]-1H-imidazole
CFAMM00382011 CHEMBL1744292 Bioactive (E)-but-2-enedioic acid;5-(thiophen-3-ylmethyl)-1H-imidazole
CFAMM00382010 CHEMBL1744263 Bioactive (E)-but-2-enedioic acid;5-[1-(4-ethylthiophen-3-yl)ethyl]-1H-imidazole
CFAMM00382016 CHEMBL1744289 Bioactive 5-[(4-bromothiophen-3-yl)methyl]-1H-imidazole;(E)-but-2-enedioic acid
CFAMM00382015 CHEMBL1744278 Bioactive (E)-but-2-enedioic acid;5-[(4-ethylthiophen-3-yl)methyl]-1H-imidazole
CFAMM00382014 CHEMBL1788145 Bioactive 5-[1-(4-bromothiophen-3-yl)ethyl]-1H-imidazole;(E)-but-2-enedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26200 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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