CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7689
Family Name Growth factor receptor-bound protein 2 ligand [4-[[(2S,5S,9S,11E)-5-(2-amino-2-oxoethyl)-2-methyl-9-(naphthalen-1-ylmethyl)-3,6,15-trioxo-13-[4-(phosphonomethyl)phenyl]-1,4,7-triazacyclopentadec-11-en-2-yl]methyl]phenyl]phosphonic acid family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00382261 Functional Category Bioactive
Superfamily Growth factor receptor-bound protein 2 Binder Superfamily
Class Class 4546

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 F... 3 51
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Endothelin-converting enzyme 1 Inhibitor PO3 2-leu-nal-o-3k Fa... 3 26
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Neprilysin and Aminopeptidase N inhibitor (2S)-2-[[(2S)-2-[[[a... 13 1
Renin and Cathepsin D inhibitor (3S)-4-[[6-acetamido-2-[[3-nap... 6 26
Neprilysin inhibitor SureCN489232 family 3 9
Growth factor receptor-bound protein 2 ligand 2-[(9S,10S,11E,1... 5 14
Tryptase alpha/beta-1 inhibitor methyl 3-[3-(aminomethyl)pheny... 1 3
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 5 3
Collagenase 3 and Interstitial collagenase inhibitor (4-benzyl... 2 0
Melanocortin receptor 4 and Melanocortin receptor 3 ligand (2S... 2 0
Neutrophil collagenase and Macrophage metalloelastase inhibito... 1 0


External ID

Functional Category

Molecule Name

CFAMM00382261 CHEMBL175456 Bioactive [4-[[(2S,5S,9S,11E)-5-(2-amino-2-oxoethyl)-2-methyl-9-(naphthalen-1-ylmethyl)-3,6,15-trioxo-13-[4-(phosphonomethyl)phenyl]-1,4,7-triazacyclopentadec-11-en-2-yl]methyl]phenyl]phosphonic acid
CFAMM00382259 CHEMBL55627 Bioactive NSC708238

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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