CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7693
Family Name Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit beta-3 ligand 6,6-dimethyl-3-methylsulfanyl-1-pyridin-4-yl-5,7-dihydro-2-benzothiophen-4-one family
No. of Seeds 4 No. of Other Members 11
Family Centroid CFAMM00382287 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-aminobutyric acid receptor subunit gamma-2 Binder Superfamily 8
Class Class 2366

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Cytochrome P450 3A4 Inhibitor 3-(3-methylthiophen-2-yl)pyridin... 5 27
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 4 2
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Cyclin-dependent kinase 8 and Cyclin-dependent kinase 5 inhibi... 1 6
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 4
Intercellular adhesion molecule 1 and E-selectin inhibitor Sur... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 4 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382292 CHEMBL17698 Bioactive SureCN7363953
CFAMM00382291 CHEMBL17547 Bioactive SureCN7373054
CFAMM00382282 CHEMBL17574 Bioactive SureCN7442376
CFAMM00382287 CHEMBL276508 Bioactive 6,6-dimethyl-3-methylsulfanyl-1-pyridin-4-yl-5,7-dihydro-2-benzothiophen-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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