CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7694
Family Name Serine/threonine-protein kinase Chk2 inhibitor SureCN3919556 family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00382303 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) Benzimidazole-4-carboxamide Superfamily
Class Class 1456

Cousin Family NamesSeedsMembers
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-... 2 15
Thyroid hormone receptor beta ligand CHEMBL1325165 family 1 6
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
NS5B protein inhibitor (2E)-1-cyclohexyl-2-(2-fluoro-4-oxocycl... 2 10
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Plasma kallikrein and Coagulation factor VII inhibitor 2-[(3E)... 15 49
Smoothened homolog inhibitor N-[3-(1H-benzimidazol-2-yl)phenyl... 2 1
Type-1 angiotensin II receptor ligand N-[2-(3-methoxyphenyl)et... 2 0
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Vascular endothelial growth factor receptor 2 and Fibroblast g... 1 6
Platelet-derived growth factor receptor alpha and Vascular end... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 16 0
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Smoothened homolog and Sonic hedgehog protein inhibitor 496794... 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07C5JC family 1 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-0763... 1 1


External ID

Functional Category

Molecule Name

CFAMM00382304 CHEMBL179717 Bioactive SureCN3925959
CFAMM00382303 CHEMBL359881 Bioactive SureCN3919556
CFAMM00382302 CHEMBL175553 Bioactive SureCN3918707
CFAMM00382307 CHEMBL175472 Bioactive SureCN3917059

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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