CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7699
Family Name Gonadotropin-releasing hormone receptor ligand SureCN5756131 family
No. of Seeds 5 No. of Other Members 7
Family Centroid CFAMM00382397 Functional Category Bioactive
Superfamily Translocator protein and Gonadotropin-releasing hormone receptor Binder Superfamily
Class Class 2417

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Inosine-5'-monophosphate dehydrogenase Inhibitor VX-148 Family 2 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 6
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 3 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 2
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 9 37
Transient receptor potential cation channel subfamily V member... 3 15
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family 3 3
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2K family 2 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 4 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
Melanin-concentrating hormone receptor 1 ligand 3-[4-fluoro-3-... 3 7
Motilin receptor ligand SureCN14564469 family 1 6
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
Translocator protein inhibitor CHEMBL2332259 family 2 0
C-X-C chemokine receptor type 3 ligand 1-[1-[(9-acetyl-9-azabi... 1 0
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 1 0
Sterol O-acyltransferase 1 inhibitor SureCN6152927 family 7 3
Histamine H3 receptor ligand AGN-PC-07ZCFA family 1 0
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752KC... 3 3
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
P2X purinoceptor 7 inhibitor SureCN3722920 family 4 0
C-X-C chemokine receptor type 3 ligand 1-[1-[[(1S,5R)-6,6-dime... 2 3
Cholinesterase inhibitor (13-methyl-5,6,8,13a-tetrahydroisoqui... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 6-[2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382399 CHEMBL368511 Bioactive 1-[(2R)-2-amino-2-phenylethyl]-3-[(2-bromo-6-fluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-1,3,5-triazinane-2,4,6-trione
CFAMM00382391 CHEMBL180372 Bioactive 1-[(2R)-2-amino-2-phenylethyl]-3-[(2-chloro-6-fluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-1,3,5-triazinane-2,4,6-trione
CFAMM00382397 CHEMBL367388 Bioactive SureCN5756131
CFAMM00382389 CHEMBL175711 Bioactive 1-[(2R)-2-amino-2-phenylethyl]-3-(2-fluoro-3-methoxyphenyl)-5-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-1,3,5-triazinane-2,4,6-trione
CFAMM00382400 CHEMBL2113012 Bioactive 3-[(2R)-2-amino-2-phenylethyl]-1-[(2,6-difluorophenyl)methyl]-5-(3-methoxyphenyl)-1,3,5-triazinane-2,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26224 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543