CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7703
Family Name Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cyanophenyl)phenyl]-1-ethylpiperidin-4-yl]methyl]-3-(3,5-dichlorophenyl)urea family
No. of Seeds 14 No. of Other Members 23
Family Centroid CFAMM00382446 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and cAMP-specific 3',5'-cyclic phosphodiesterase 4D Binder Superfamily
Class Class 3520

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C8 inhib... 6 5
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 13 6
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Melanin-concentrating hormone receptor 1 ligand SureCN3845324 ... 7 4
Melanin-concentrating hormone receptor 1 ligand 1-[4-(3-cyanop... 4 9
Melanin-concentrating hormone receptor 1 ligand SureCN14265737... 2 0
Melanin-concentrating hormone receptor 1 ligand N-[2-[4-(3-cya... 3 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand SureCN14265866... 11 2
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Melanin-concentrating hormone receptor 1 ligand AGN-PC-0762XZ ... 3 1
Melanin-concentrating hormone receptor 1 ligand SureCN13918038... 6 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00CYMY ... 1 0
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 4 0
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 5
Melanin-concentrating hormone receptor 1 ligand 1-[4-chloro-3-... 1 1
Neuropeptide Y receptor type 5 ligand SureCN6214451 family 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 3
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
Melanin-concentrating hormone receptor 1 ligand 2-[1-(1-cyclop... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382442 CHEMBL176219 Bioactive SureCN3165449
CFAMM00382441 CHEMBL179326 Bioactive 1-[2-[4-(3-cyanophenyl)phenyl]-4-(dimethylamino)butyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382421 CHEMBL361392 Bioactive SureCN13451986
CFAMM00382453 CHEMBL179425 Bioactive 1-[2-[4-(3-cyanophenyl)phenyl]-4-(ethylamino)butyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382420 CHEMBL178997 Bioactive SureCN13452025
CFAMM00382446 CHEMBL175783 Bioactive 1-[[4-[4-(3-cyanophenyl)phenyl]-1-ethylpiperidin-4-yl]methyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382426 CHEMBL176088 Bioactive AGN-PC-00FG7Q
CFAMM00382419 CHEMBL2112988 Bioactive 1-[2-[4-(3-cyanophenyl)phenyl]-4-piperidin-1-ylbutyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382437 CHEMBL179437 Bioactive 1-[[4-[4-(3-cyanophenyl)phenyl]-1-cyclohexylpiperidin-4-yl]methyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382417 CHEMBL176208 Bioactive 1-[[4-[4-(3-cyanophenyl)phenyl]-1-propan-2-ylpiperidin-4-yl]methyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382430 CHEMBL368417 Bioactive 1-[2-[4-(3-cyanophenyl)phenyl]-4-(propan-2-ylamino)butyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382443 CHEMBL179493 Bioactive 1-[2-[4-(3-cyanophenyl)phenyl]-4-(methylamino)butyl]-3-(3,5-dichlorophenyl)urea
CFAMM00382423 CHEMBL176220 Bioactive SureCN13451984
CFAMM00382436 CHEMBL176159 Bioactive SureCN13451763

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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