CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7707
Family Name Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit beta-3 ligand AGN-PC-00FEF7 family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00168726 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-aminobutyric acid receptor subunit gamma-2 Ligand TPA-023 Superfamily
Class Class 855

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Ibrutinib family 2 27
Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 37
Corticotropin-releasing factor receptor 1 Ligand BMS-561388 Fa... 10 16
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 11
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 10 3
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 31 11
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 4 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 9 19
Translocator protein inhibitor AGN-PC-080ILF family 9 3
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 5
Leukotriene B4 receptor 1 ligand AGN-PC-075N6M family 2 4
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 4
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 1
Adenosine receptor A2a ligand 7-(3,4-dimethoxyphenyl)-2-(furan... 6 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 6 0
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 7 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 4
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 7 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 4 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand 1-... 8 6
Estrogen receptor and Estrogen receptor beta ligand 4-[3-[4-(2... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand 5-[(7S... 6 1
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 0
Hepatocyte growth factor receptor ligand 6-[(1S)-1-[6-(2,3-dih... 1 5
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 29 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 2 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 4 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Oxytocin receptor ligand AGN-PC-07C71T family 3 2
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor AGN-PC... 2 0
Acyl-CoA desaturase 1 inhibitor Pyridazine, 3-[4-(2-ethylpheno... 4 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382482 CHEMBL416659 Bioactive AGN-PC-009LQJ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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