CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7711
Family Name Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cyanophenyl)phenyl]-4-(dimethylamino)butyl]-3-(3,5-difluorophenyl)urea family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00382507 Functional Category Bioactive
Superfamily Substance-P receptor and C-C chemokine receptor type 3 Binder Superfamily
Class Class 2044

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-[bis(4-iodophenyl)methyl]-3-(4... 4 13
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Tyrosinase Inhibitor 1-hydroxy-3-(4-(trifluoromethyl)phenyl)ur... 2 3
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
C-C chemokine receptor type 3 ligand 4-[(3-acetylphenyl)carbam... 3 4
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 13 6
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 2 3
Melanin-concentrating hormone receptor 1 ligand 3-(3-bromophen... 4 0
C-C chemokine receptor type 3 ligand SureCN6703027 family 2 1
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Melanin-concentrating hormone receptor 1 ligand SureCN3845324 ... 7 4
Melanin-concentrating hormone receptor 1 ligand 1-[4-(3-cyanop... 4 9
Melanin-concentrating hormone receptor 1 ligand SureCN14265737... 2 0
Melanin-concentrating hormone receptor 1 ligand N-[2-[4-(3-cya... 3 9
C-C chemokine receptor type 3 ligand 4-(5-amino-2-oxo-3H-benzi... 1 0
Melanin-concentrating hormone receptor 1 ligand SureCN14101999... 3 0
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Melanin-concentrating hormone receptor 1 ligand AGN-PC-0762XZ ... 3 1
C-C chemokine receptor type 3 ligand AGN-PC-073RIP family 2 4
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Melanin-concentrating hormone receptor 1 ligand 1-[4-chloro-3-... 1 1
C-C chemokine receptor type 5 ligand AC1L9YPM family 3 6
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 0
Sterol O-acyltransferase 1 inhibitor SureCN7565101 family 2 10
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9352718 f... 2 3
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN13328411 ... 4 2
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382503 CHEMBL424961 Bioactive 1-[2-[4-(3-cyanophenyl)phenyl]-4-(dimethylamino)butyl]-3-(3,4-difluorophenyl)urea
CFAMM00382507 CHEMBL175993 Bioactive 1-[2-[4-(3-cyanophenyl)phenyl]-4-(dimethylamino)butyl]-3-(3,5-difluorophenyl)urea
CFAMM00382505 CHEMBL368888 Bioactive SureCN13451731

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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