CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7716
Family Name Potassium voltage-gated channel subfamily H member 2 and Melanin-concentrating hormone receptor 1 ligand N-(3-chlorophenyl)-2-[(3R,4S)-1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-methoxyphenyl)pyrrolidin-3-yl]acetamide family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00382597 Functional Category Bioactive with Natural Product
Superfamily Melanin-concentrating hormone receptor 1 and Cyclic AMP-specific phosphodiesterase SSPDE4A1A Binder Superfamily
Class Class 2065

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 2 0
Endothelin B receptor and Endothelin-1 receptor ligand SureCN8... 6 4
Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chlor... 1 4
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Cathepsin D and Plasmepsin-2 inhibitor 1-acetyl-N-[2-(1,3-benz... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382597 CHEMBL1760234 Bioactive N-(3-chlorophenyl)-2-[(3R,4S)-1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-methoxyphenyl)pyrrolidin-3-yl]acetamide
CFAMM00382601 CHEMBL1760247 Bioactive N-(3-chlorophenyl)-2-[(3R,4S)-1-[2-(1,1-dioxothian-4-yl)ethyl]-4-(4-methoxyphenyl)pyrrolidin-3-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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